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Changde Yungang Biotechnology Co., Ltd

Country: China (Mainland)

Business Type:Manufacturers

Ms.Li

Tel: +86-736-7391178

Mobile: +86 18507362893

Tel: +86-736-7391178

Fax: +86-736-7382308

URL: http://www.cdyg.com

Province/state: Hunan

City: Changde

Street: Qiaonan Industrial Park, Changde City, Hunan Province

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with fast delivery Chenodeoxycholic Acid good supplier/Hot sale Hot sale

CAS NO.474-25-9

  • Min.Order: 1 Kilogram
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  • ProName: with fast delivery Chenodeoxycholic Ac...
  • CasNo: 474-25-9
  • Molecular Formula: C24H40O4
  • Appearance: White or yellowish crystallization pow...
  • Application: Mainly used in the synthesis of ursode...
  • DeliveryTime: prompt goods
  • PackAge: 25KG/Drum
  • Port: shanghai
  • ProductionCapacity: 10 Metric Ton/Month
  • Purity: HPLC≥98.0% ；HPLC≥95.0% ；HPLC≥90.0%
  • Storage: keep in closed vessel.
  • LimitNum: 1 Kilogram

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with fast delivery Chenodeoxycholic Acid good supplier/Hot sale Hot sale

Properties 

Appearance & Physical State: white to off-white crystalline powder
Density: 1.128g/cm3
Melting Point: 167-171ºC
Boiling Point: 547.1ºC at 760 mmHg
Flash Point: 298.8ºC
Refractive Index: 1.558
Water Solubility: PRACTICALLY INSOLUBLE
Storage Condition: Store in a cool, dry place. Store in a tightly closed container.
Safety Info 
RTECS: FZ1980000
Safety Statements: S36/37-S45
HS Code: 2918990090
WGK Germany: 2
Risk Statements: R63
Hazard Codes: Xn

We are the earliest factory for extraction of cdca from porcine gallbladder. Our company mainly from pig gallbladder and poultry gallbladder, extraction of pig gallbladder technology is an international initiative,  it is the core technology of our company.

 

Chenodeoxycholic acid Basic information
Product Name: Chenodeoxycholic acid
Synonyms: URSODEOXYCHOLOC ACID;3,7-dihydroxy-,(3-alpha,5-beta,7-alpha)-cholan-24-oicaci;3,7-dihydroxy-,(3alpha,5beta,7alpha)-cholan-24-oicaci;3,7-Dihydroxy-5-Cholanicacid;3-alpha,7-alpha-dihydroxy-5-beta-cholan-24-oicaci;3-alpha,7-alpha-dihydroxy-5-beta-cholan-24-oicacid;3-alpha,7-alpha-dihydroxycholanicacid;3-alpha,7-alpha-dihydroxycholansaeure
CAS: 474-25-9
MF: C24H40O4
MW: 392.57
EINECS: 207-481-8
Product Categories: Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Intracellular receptor
Mol File: 474-25-9.mol
Chenodeoxycholic acid Structure
Description 
Chenodeoxycholic acid (also known as chenodesoxycholic acid, chenocholic acid and 3α,7α-dihydroxy-5β-cholan-24-oic acid) is a bile acid. It occurs as a white crystalline substance insoluble in water but soluble in alcohol and acetic acid, with melting point at 165-167°C. Salts of this carboxylic acid are called chenodeoxycholates. Chenodeoxycholic acid is one of the main bile acids produced by the liver.
It was first isolated from the bile of the domestic goose, which gives it the "cheno" portion of its name (Greek: χ?ν = goose).
Chenodeoxycholic acid and cholic acid are the two primary bile acids in humans. Some other mammals have muricholic acid or deoxycholic acid rather than chenodeoxycholic acid.
Chenodeoxycholic acid is synthesized in the liver from cholesterol by a process which involves several enzymatic steps. Like other bile acids, it can be conjugated in the liver with taurine or glycine, forming taurochenodeoxycholate or glycochenodeoxycholate. Conjugation results in a lower pKa. This means the conjugated bile acids are ionized at the usual pH in the intestine and will stay in the gastrointestinal tract until reaching the ileum where most will be reabsorbed. Bile acids form micelles which facilitate lipid digestion. After absorption, they are taken up by the liver and resecreted, so undergoing an enterohepatic circulation. Unabsorbed chenodeoxycholic acid can be metabolised by bacteria in the colon to form the secondary bile acid known as lithocholic acid.
Choendeoxycholic acid is the most potent natural bile acid at stimulating the nuclear bile acid receptor, farnesoid X receptor (FXR). The transcription of many genes is activated by FXR.

Details

Chenodeoxycholic acid Chemical Properties

Melting point  165-167 °C(lit.)
alpha  12 º (c=1, CHCl3)
Boiling point  437.26°C (rough estimate)
density  0.9985 (rough estimate)
refractive index  1.4460 (estimate)
Fp  9℃
storage temp.  Refrigerator
solubility  PRACTICALLY INSOLUBLE
form  Powder
pka pKa 4.34 (Uncertain)
color  White to off-white
Water Solubility  PRACTICALLY INSOLUBLE
Merck  13,2062
InChIKey RUDATBOHQWOJDD-BSWAIDMHSA-N
CAS DataBase Reference 474-25-9(CAS DataBase Reference)
EPA Substance Registry System Cholan-24-oic acid, 3,7-dihydroxy-, (3.alpha.,5.beta.,7.alpha.)- (474-25-9)
Safety Information
Hazard Codes  Xn
Risk Statements  63
Safety Statements  22-24/25-45-36/37
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  2
RTECS  FZ1980000
HS Code  29181990
Bile salts series:It is the most commonly used selective inhibitor in culture,we have Bile salts of cow ,Bile salts of pig ,Bile salts #3,Bile powder of pig
 Cholic acid (Breeding)，Bile acid is a kind of functional feed additive with natural biological activity to promote fat absorption. It has been widely used in livestock and aquaculture. It can make up for the deficiency of bile acid secretion in animals and protect the liver and bile health of animals. Improving the performance of animal production, 
L-2-Aminobutyric acid  which is the main raw material of new antiepileptic drug levetiracetam.
 
 

About us

Changde Yungang Biotechnology Co., Ltd. is an export-oriented hi-tech enterprise; we are mainly engaged in the research, development, manufacturing and trade of pharmaceutical intermediates. Staring from the innovations of technology and product, Yungang is striving to develop new products and technologies; we are working hard for promoting its competitive force and sustainable developing capacity. Led by Deng Jiaguo (the founder and general manager of Yungang), we adopt the latest technologies to produce Ursodeoxycholic acid and chenodeoxycholic acid serial products. The preparation method of chenodeoxycholic acid has passed the authentication of technical achievement of our province and got several Chinese patents. At present, our Ursodeoxycholic acid can meet the standards of CP, USP and JP; Meanwhile, we also offer other specifications of products to customers with special requirements. Now, our main products including Ursodeoxycholic acid, chenodeoxycholic acid, Hyodeoxycholic acid, Cholic acid, Deoxycholic acid, Dehydrocholic acid and bacteria quarantine series such as bile salts of cow, bile salts 3, bile salts of fowl, cattle goll powder, bile powder of pig, deoxidization sodium cholate, and so on. Relying on the excellent strength of Chinese hi-tech enterprise and upholding such idea and culture spirit of "Honest, Unity, Be practical, be enterprising, be creative", we are working for customers' demands. Yungang looks forward to cooperating with you.

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