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Changde Yungang Biotechnology Co., Ltd

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high purity 81-25-4 Best price in stock

CAS NO.81-25-4

  • Min.Order: 25 Kilogram
  • Payment Terms: L/C,T/T
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  • high purity 81-25-4
  • 81-25-4 in stock
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Quick Details

  • ProName: high purity 81-25-4 Best price in sto...
  • CasNo: 81-25-4
  • Molecular Formula: C24H40O5
  • Appearance: White or almost white crystalline powd...
  • Application: Effect and use: increase blood lipid c...
  • DeliveryTime: prompt goods
  • Port: shanghai
  • ProductionCapacity: 8000 Kilogram/Day
  • Purity: HPLC≥98.0%.
  • Storage: Keep in closed vessel & store in room ...
  • LimitNum: 25 Kilogram

Superiority

high purity  81-25-4 Best price in stock

Cholic acid is a kind of sterols, is four major human one of the most abundant content of bile acid, derived from it and gca taurocholic acid is the main human bile acid. Liver secretion to bile in the bile salt (sodium salt of bile acid) is a powerful emulsifier.

After bile flow through the upper small intestine, bile salt emulsifying fat, help the digestion and absorption. In the emulsifying fat globules fatty acid glyceride and absorbed by the lower part of the small intestine, bile salt is absorbed by weight. They returned to the liver and be reused, so total bile salt circulation between liver and small intestine.
Cholic acid is synthesized from liver, bile into the duodenum, as one part of the digestive juice, can promote digestion and absorption of lipid.

   Certification of Analysis

 

 

TEST
SPECIFICATION
RESULT
Appearance
White to off-white crystals
White crystals
Identification
1-HNMR: Consistent with the standard
Conforms
IR: The IR absorption spectrum of the sample must be concordant with test Standard.
Conforms
HPLC: The HPLC spectrum of the sample must be concordant with the standard substance.
Conforms
Residue on ignition
NMT 0.2%
0.02%
Water
NMT 2.0%
0.06%
Heavy Metals
NMT 20ppm
5ppm
Related Substance
Impurity A: NMT 0.2%
0.07%
Impurity B: NMT 0.15%
0.03%
Impurity C: NMT 0.15%
0.07%
Any other impurity: NMT 0.10%
N.D.
Total impurities: NMT 1.0%
0.17%
Residual Solvents
Methanol: NMT 0.3%
N.D.
Ethanol: NMT 0.5%
N.D.
Ethyl acetate: NMT 0.5%
N.D.
Assay(By HPLC)
98.0%~102%
99.84%
Storage
Store in a tightly closed container in a cool and dry place, below 20℃.
Conclusion
Confirm to enterprise standard

 

                          Function&Application

 

 

Application

(1) It can emulsify fat and improve its function of digestion as a kind of organic acid.
(2) It can be applied in emulgator.
(3) It can be applied in the research of biochemistry as a kind of medical intermediate.
(4) It can be applied in non ion-modified detergent to extract membrane protein.
(5) It is mainly used as medicine raw materials.
(6) The cholesterol is still the raw material of cosmetics, and a good surfactant of medicine products. It can also be used for additive of animal feed.

Function

(1) It can treat cholecystitis, the lack of bile, intestinal indigestion and gallstones etc.
(2) It can prevent and treat liver diseases.
(3) It is a kind of organic acid and can be used to produce vitamin D2 and D3.

 

 

 

NAME: Cholic Acid HPLC≥ 98.0% CHEMICAL NAME: 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid FORMULA :C24H40O5 MOLECULAR WEIGHT : 408.58 CAS …

Details

Cholic acid Basic information
Chemical properties Uses Identification test Analysis of the content Toxicity Production methods
Product Name: Cholic acid
Synonyms: Ursodeoxycholic Acid EP Impurity B;(4R)-4-((3R,5S,7R,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid;3,7,12-Trihydroxy-cholan-24-oic acid;Cholic acid from pure ox bile;Cholic acid from bovine and sheep;Chenodeoxycholic Acid Impurity 2;5beta-Cholan-24-oic acid, 3alpha,7alpha,12alpha-trihydroxy-;Cholan-24-oic acid, 3,7,12-trihydroxy-, (3alpha,5beta,7alpha,12alpha)-
CAS: 81-25-4
MF: C24H40O5
MW: 408.57
EINECS: 201-337-8
Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids
Mol File: 81-25-4.mol
Cholic acid Structure
Cholic acid Chemical Properties
Melting point  200-201 °C(lit.)
alpha  36 º (c=0.6, 95% EtOH)
Boiling point  449.08°C (rough estimate)
density  1.0310 (rough estimate)
refractive index  1.5800 (estimate)
Fp  9℃
storage temp.  Store at RT.
solubility  methanol: 0.1 g/mL, clear
pka 4.98(at 20℃)
Water Solubility  0.28 g/L (15 ºC)
Merck  14,2203
BRN  2822009
CAS DataBase Reference 81-25-4(CAS DataBase Reference)
NIST Chemistry Reference Cholic acid(81-25-4)
EPA Substance Registry System Cholan-24-oic acid, 3,7,12-trihydroxy-, (3.alpha.,5.beta.,7.alpha., 12.alpha.)-(81-25-4)

 

NAME: Cholic Acid HPLC≥ 98.0% CHEMICAL NAME: 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid FORMULA :C24H40O5 MOLECULAR WEIGHT : 408.58 CAS NUMBER: 81-25-4

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